MHub/IDC/Grand Challenge algorithm exchange

The MHub/IDC/Grand Challenge algorithm exchange project is a collaboration between Radboudumc, MHub, and Imaging Data Commons (IDC), aimed at porting ten deep learning algorithms available at Grand ChallengeGrand Challenge platform to the open-source MHub platform and is part of a larger project investigating data and algorithm exchange between the three involved parties. The project was financed by the National Institute of Health (NIH) through the Leidos Biomedical Research Inc as subcontract through the Brigham and Women’s hospital.

MHub is a comprehensive repository of self-contained deep learning models designed for a wide range of applications in the medical and medical imaging domains, with a strong focus on cutting-edge advancements and reproducible science. Each MHub model is packaged as an MHub container, which is bundled inside a Docker container, complete with all necessary system dependencies and model weights. This setup allows you to run any model with a single docker run command.

One of the major advantages of MHub containers is their standardized yet flexible input and output interface, enabling you to prepare your data once and use it across any MHub model. Additionally, the repository offers extensive documentation for each algorithm, making it easier to understand the model’s design, expected inputs and outputs, potential caveats, and more.

Grand Challenge is a platform dedicated to the end-to-end development of machine learning solutions in biomedical imaging. A core component of Grand Challenge is the concept of an Algorithm, which encapsulates all the necessary code, models, and dependencies for running a deep learning algorithm. These Algorithms are implemented as Docker containers with predefined input and output interfaces, allowing users to implement deep learning pipelines in any framework and run them on any image available through Grand Challenge.

In this project, ten algorithms from Grand Challenge have been successfully ported to the MHub repository. Each model has been re-implemented as a self-contained Docker file within the MHub framework and is thoroughly annotated for ease of understanding and use. A detailed list of the implemented models in the MHub repository can be found below:

People

Leonard Nürnberg

Leonard Nürnberg

PhD Student

Harvard AIM | Maastricht University

Dennis Bontempi

Dennis Bontempi

Postdoctoral Researcher

University of Lausanne

Bram van Ginneken

Bram van Ginneken

Professor, Scientific Co-Director

Diagnostic Image Analysis Group

Andrey Fedorov

Andrey Fedorov

Lead Scientist | Associate Professor in Radiology

Brigham and Women's Hospital | Harvard Medical School

Hugo Aerts

Hugo Aerts

Director

Harvard AIM

Henkjan Huisman

Henkjan Huisman

Associate Professor

Diagnostic Image Analysis Group

Ajay Patel

Ajay Patel

RTC Deep Learning

Sil van de Leemput

Sil van de Leemput

Research Scientist RTC Deep Learning

Miriam Groeneveld

Miriam Groeneveld

Research Software Engineer

Computational Pathology Group

Keyvan Farahani

Keyvan Farahani

Senior Data Science, Imaging, and AI Program Director

National Heart, Lung, and Blood Institute, NIH

Linmin Pei

Linmin Pei

None

None

Ulrike Wagner

Ulrike Wagner

None

None

Granger Sutton

Granger Sutton

Data Scientist, NCI

The National Institutes of Health, NIH